Best Week Ever: 4x24
Best Episode Ever: 100th Episode
Willard Scott wishes Best Week Ever a happy 100 episodes, Mel Gibson, Project Runway, Lindsay Lohan, Celebrities!!!; Sizzler: Tori Spelling, Boy George; OK Go: Here It Goes Again; In Case You Missed It: Yaz, The View, Danica Patrick, Microsoft Voice Recognition Software; Best Week Ever: Pam Anderson & Kid Rock
4 - 1January 13th, 2006 Jan. 13, 2006- 4 - 2Golden Globes Jan. 20, 2006
- 4 - 3Sundance Jan. 27, 2006
- 4 - 4February 3rd, 2006 Feb. 03, 2006
- 4 - 5February 17th, 2006 Feb. 17, 2006
- 4 - 6February 24th, 2006 Feb. 24, 2006
- 4 - 7March 3rd, 2006 Mar. 03, 2006
- 4 - 8March 10th, 2006 Mar. 10, 2006
- 4 - 9March 24th, 2006 Mar. 24, 2006
- 4 - 10March 31, 2006 Mar. 31, 2006
- 4 - 11April 7th, 2006 Apr. 07, 2006
- 4 - 12April 14th, 2006 Apr. 14, 2006
- 4 - 13April 21st, 2006 Apr. 21, 2006
- 4 - 14May 5th, 2006 May. 05, 2006
- 4 - 15May 12th, 2006 May. 12, 2006
- 4 - 16May 26th, 2006 May. 26, 2006
- 4 - 17June 9th, 2006 Jun. 09, 2006
- 4 - 18June 16th, 2006 Jun. 16, 2006
- 4 - 19June 23rd, 2006 Jun. 23, 2006
- 4 - 20July 7th, 2006 Jul. 07, 2006
- 4 - 21July 14th, 2006 Jul. 14, 2006
- 4 - 22July 21, 2006 Jul. 21, 2006
- 4 - 23July 28th, 2006 Jul. 28, 2006
- 4 - 24Best Episode Ever: 100th Episode Aug. 04, 2006
- 4 - 25July 28th Jul. 28, 2006
- 4 - 26August 4th Aug. 04, 2006