Lopez Tonight: 1x72
James Marsden, Reggie Miller
1 - 1Eva Longoria, Kobe Bryant, Ellen DeGeneres Nov. 09, 2009- 1 - 2Jamie Foxx, Marc Anthony Nov. 10, 2009
- 1 - 4Larry David, Kelly Osbourne Nov. 12, 2009
- 1 - 5Charlie Sheen, Demi Lovato Nov. 16, 2009
- 1 - 6Andy Garcia, The Real Housewives of Orange County Nov. 17, 2009
- 1 - 7Andy Garcia, Real Housewives of OC, Justin Bieber Nov. 17, 2009
- 1 - 8Ted Danson, Bill Engvall Nov. 19, 2009
- 1 - 9Eva Mendes, Craig Robinson Nov. 23, 2009
- 1 - 12Sandra Bullock, Derek Luke, Shakira Nov. 24, 2009
- 1 - 16Laurence Fishburne, Olivia Munn Dec. 03, 2009
- 1 - 17Taye Diggs, Kaley Kuoko, Ruben Paul Dec. 02, 2009
- 1 - 18Laurence Fishburne , Olivia Munn, Los Lobos Dec. 03, 2009
- 1 - 19Kathy Griffin, Rico Rodriguez Dec. 07, 2009
- 1 - 20Hillary Duff, Scott Bakula Dec. 10, 2009
- 1 - 21Cedric the Entertainer, Corona Girl & Morrissey Dec. 09, 2009
- 1 - 22Hilary Duff, Scott Bakula & Rudy Moreno Dec. 10, 2009
- 1 - 23Mariah Carey, David Beckham Dec. 16, 2009
- 1 - 24"George Lopez" Reunion Dec. 15, 2009
- 1 - 25David Beckham & Mariah Carey Dec. 16, 2009
- 1 - 26Ray Romano, Lake Bell, Mariah Carey & the Cast of Dec. 16, 2009
- 1 - 27Larry David, Lisa Lampanelli, Jay Sean, Birdman Jan. 04, 2010
- 1 - 28Ted Danson, Bill Engvall, Orianthi Sep. 19, 2025
- 1 - 29Jamie Foxx, Marc Anthony Sep. 19, 2025
- 1 - 30Sandra Bullock, Derek Luke, Shakira, Chola Girl Sep. 19, 2025
- 1 - 31Jackie Chan, Ke$ha Jan. 11, 2010
- 1 - 32Samuel L. Jackson, Omarion Jan. 21, 2010
- 1 - 33Charles Barkley Jan. 13, 2010
- 1 - 34Snoop Dogg, Saoirse Ronan Jan. 14, 2010
- 1 - 35Amber Valletta, Mark Valley Jan. 18, 2010
- 1 - 36Brendan Fraser, Khloe and Kourtney Kardashian Jan. 19, 2010
- 1 - 37Tyrese Gibson, Betty White Jan. 20, 2010
- 1 - 38Samuel L, Jackson, Dianna Agron Jan. 21, 2010
- 1 - 39Cheech and Chong, Regina King Jan. 25, 2010
- 1 - 40Sofía Vergara, James Van Der Beek Jan. 26, 2010
- 1 - 41Jamie Foxx and Garry Marshall Feb. 08, 2010
- 1 - 42Topher Grace, Jewel Feb. 09, 2010
- 1 - 43Ashton Kutcher, Emma Roberts, Carter Jenkins Feb. 10, 2010
- 1 - 44Jennifer Garner, Hector Elizondo and Steel Magnolia Feb. 11, 2010
- 1 - 45Season 1, Episode 45 Feb. 15, 2010
- 1 - 46Season 1, Episode 46 Feb. 16, 2010
- 1 - 47Snoop Dogg; Saoirse Ronan Feb. 17, 2010
- 1 - 48
- 1 - 50Freddie Prinze Jr., Steve Austin Mar. 10, 2010
- 1 - 51Lenny Kravitz, Khloe & Lamar Odom, Emilio Estefan Mar. 10, 2010
- 1 - 52Ozzy Osbourne, Kendra & Hank Baskett, Alonzo Mourning Mar. 11, 2010
- 1 - 53
- 1 - 54Dominic Monaghan, Kat Von D, Joe Bonamassa Mar. 16, 2010
- 1 - 55Wanda Sykes, Peter Facinelli, Loni Love Mar. 17, 2010
- 1 - 56
- 1 - 57
- 1 - 58
- 1 - 59Eric Andre, Eva Longoria, Sinbad Mar. 24, 2010
- 1 - 60Chad Ochocinco, Johnny Weir Mar. 25, 2010
- 1 - 61Annie Wersching, Foreigner, Snoop Dogg Mar. 29, 2010
- 1 - 62Clark Duke, Ludacris Mar. 30, 2010
- 1 - 63Johnny Sanchez, Omar Epps, Wendy Williams Mar. 31, 2010
- 1 - 64Ron Artest, Usher Apr. 01, 2010
- 1 - 65
- 1 - 66Brandy, Ray J Apr. 06, 2010
- 1 - 67Bruno Tonioli, George Wallace, Taraji P. Henson Apr. 07, 2010
- 1 - 68Slash, Zachary Levi Apr. 08, 2010
- 1 - 69Chris Rock, Oscar De La Hoya, Sugar Shane Mosley Apr. 12, 2010
- 1 - 70Audrina Patridge, Benjamin Bratt, Bryan Kellen Apr. 13, 2010
- 1 - 71Luke Wilson, Monica Apr. 14, 2010
- 1 - 72James Marsden, Reggie Miller Apr. 15, 2010
- 1 - 73Kara Dioguardi, Cheech Marin & Tommy Chong, Jason Reeves Apr. 19, 2010
- 1 - 74Angela Kinsey, Brendan Fraser, Jason Aldean Apr. 20, 2010
- 1 - 75Chris Evans, Idris Elba, Lowell Sanders, Zoe Saldana Apr. 21, 2010
- 1 - 76Jennifer Lopez, Ken Jeong, Ozomatli Apr. 22, 2010
- 1 - 77Amare Stoudemire Feb. 21, 2011
- 1 - 78Matthew Mcconaughey Mar. 23, 2011
- 1 - 79Dallas Mavericks Sep. 19, 2025
- 1 - 80Prince Apr. 13, 2011
- 1 - 81Randy Jackson, Monica Potter, Paper Tongues May. 24, 2010
- 1 - 82Dennis Quaid, Rampage Jackson, Rashad Evans May. 25, 2010
- 1 - 83Toni Braxton May. 26, 2010
- 1 - 84Sir Ben Kingsley, Janelle Monae May. 27, 2010
- 1 - 85Drew Carey, Marisa Miller, Mike Posner May. 31, 2010
- 1 - 86Adrien Brody, Terry Crews, Hot Chelle Rae Jun. 01, 2010
- 1 - 87Cat Deeley, Charlie Murphy Jun. 02, 2010
- 1 - 88Jonah Hill, Peter Frampton Jun. 03, 2010
- 1 - 89Ashton Kucher, Hanson Jun. 07, 2010
- 1 - 90Jackie Chan, Jaden Smith, Taraji P. Henson Jun. 08, 2010
- 1 - 91Ice Cube, Alfre Woodard Jun. 09, 2010
- 1 - 92Bryan Cranston, Lil Jon featuring LMFAO Jun. 10, 2010
- 1 - 93
- 1 - 94Tim Allen, Padma Lakshmi Jun. 15, 2010
- 1 - 95Jaden Smith, Jackie Chan, Taraji P. Henson Jun. 16, 2010
- 1 - 96Rob Schneider, Mel B, Crash Kings Jun. 17, 2010
- 1 - 97Ozzy & Sharon Osbourne, Jillian Michaels Jun. 21, 2010
- 1 - 98Helen Mirren, Cedric the Entertainer, Ron Artest Jun. 22, 2010
- 1 - 99Bill Cosby, Blair Underwood, Kid 'n Play Jun. 23, 2010
- 1 - 100100th Episode - Kobe Bryant, Louis C.K. Jun. 24, 2010
- 1 - 101
- 1 - 102Kellan Lutz, Missy Peregrym, Clay Walker Jul. 13, 2010
- 1 - 103Vivica A. Fox, Big Boi Jul. 14, 2010
- 1 - 104Terrell Owens, Lifehouse Jul. 15, 2010
- 1 - 105Nicolas Cage, Dania Ramirez, Shorty Rossi Jul. 19, 2010
- 1 - 106Ali Fedotowsky, Travie McCoy & Bruno Mars Jul. 20, 2010
- 1 - 107America Ferrera, Holly Robinson Peete, Tommy Davidson Jul. 21, 2010
- 1 - 108Tiffani Thiessen, Enrique Iglesias Jul. 22, 2010
- 1 - 109Selena Gomez, Wilmer Valderrama, Rob Schneider Jul. 26, 2010
- 1 - 110Steve Carell, Maggie Q, Backstreet Boys Jul. 27, 2010
- 1 - 111Diddy, Tony Robbins, Diddy-Dirty Money Jul. 28, 2010
- 1 - 112Zac Efron Jul. 29, 2010
- 1 - 113
- 1 - 114Luke Wilson, Margaret Cho, Billy Ray Cyrus Aug. 03, 2010
- 1 - 115T.I., Idris Elba, Michael Ealy Aug. 04, 2010
- 1 - 116Will Ferrell, Elisabeth Moss Aug. 05, 2010
- 1 - 117Eva Mendes, Josh Hutcherson, Dolph Zigler Aug. 09, 2010
- 1 - 118Anna Paquin, Randy "The Viper" Orton, The Miz Aug. 10, 2010
- 1 - 119Mark Wahlberg, Bill Bellamy, David Otunga Aug. 11, 2010
- 1 - 120Gordon Ramsay, Aubrey Plaza, R-Truth Aug. 12, 2010
- 1 - 121Jason Statham, Aubrey Plaza, Wolfmother Aug. 16, 2010
- 1 - 122Dylan McDermott, Kat Von D, Meat Loaf Aug. 17, 2010
- 1 - 123
- 1 - 124Michelle Rodriguez, Ted Nugent Aug. 19, 2010
- 1 - 125Justin Long, Michael Strahan, Los Lobos Aug. 23, 2010
- 1 - 126Jason Sudeikis, Kim & Kourtney Kardashian, Korn Aug. 24, 2010
- 1 - 127Drew Barrymore, Fantasia Aug. 25, 2010
- 1 - 128Christina Applegate, Charlie Day, Lynyrd Skynyrd Aug. 26, 2010
- 1 - 129Snoop Dogg, Bethenny Frankel, Goo Goo Dolls Sep. 13, 2010
- 1 - 130
- 1 - 131
- 1 - 132Tim Gunn, Devo Sep. 16, 2010
- 1 - 133Eric Dane, Cloris Leachman, Daughtry Sep. 20, 2010
- 1 - 134Michael Franti & Spearhead Sep. 21, 2010
- 1 - 135Anthony Anderson, Morgan Spurlock, Santana & India.Arie Sep. 22, 2010
- 1 - 136
- 1 - 137LL Cool J., Kelly Osbourne & Santana with NAS Sep. 27, 2010
- 1 - 138Al Madrigal, Minka Kelly & Rob Morrow Sep. 28, 2010
- 1 - 139Magic Johnson, Sara Ramirez & Far East Movement aka FM Sep. 29, 2010
- 1 - 140Tom Bergeron & Seal Sep. 30, 2010
- 1 - 141Jim Belushi, Shakira & Neon Trees Oct. 18, 2010
- 1 - 142